Anti-D-Erythrosphingosine Antibody

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Anti-D-Erythrosphingosine Antibody

Product Name: Anti-D-Erythrosphingosine Antibody

Catalogue No.: 164518

Alternate Names: Cerebroside, Trans-D-erythro-2-Amino-4-octadecene-1,3-diol, Ceramide

Description: D-erythro-Sphingosine is the natural isomer of sphingosine and acts as a potent inhibitor of
protein kinase C, but does not inhibit protein kinase A or myosin light chain kinase, and activates casein kinase II. This compound has been shown to inhibit calmodulin-dependent enzymes, phosphatidate phosphohydrolase, ATPase, phosphocholine cytidylyltransferase (CTP), and phorbol dibutyrate binding in vitro in human platelets. D-erythro-Sphingosine is active in intact cells and has been identified as an endogenous constituent in HL-60 cells, neutrophils, rat liver, rat brain and mouse tissues.

Immunogen: D-erythrosphingosine linked to carrier.

Host: Rat.

Clonality: Polyclonal IgG.

Specificity: Universal. Cross reactivity not tested.

Concentration: 1.2mg/mL IgG.

Purity: D-erythrosphingosine affinity purified rabbit IgG to >95% (by SDS PAGE).

Format: Provided as a sterile filtered solution in PBS, pH 7.2. No other additives.

Uses: Competitive ELISA, WB. Not tested for other uses.

Storage: Store at 4oC in fridge a for short term use. Aliquot and store at -20oC or -80oC for long term storage. Avoid repeated freeze thaw cycles.

Shipping: Antibody is shipped on ice pack at ambient temperature.