Product: Anti Endothelin Receptor Alpha Polyclonal Antibody
Catalogue No.: 111024
Alternate Names: ETA, ETRA, ETAR
Description: Endothelins are considered to be very powerful vasoconstrictive substances. There are three forms of Endothelins (ET-1, -2 and –3) all of which mediate their actions via two specific G-Protein coupled receptors, ETA and ETB. Both receptors are present in the heart and in human myocardium at similar levels. The endothelin receptors differ in their ligand specificity. Currently there is increasing evidence that ET-1 may modulate mitogenesis, apoptosis, angiogenesis tumor invasion and the development of metastases.
Immunogen: C terminal peptide of Endothelin Receptor Alpha
Purity: Peptide affinity purified antibody. >90% pure by SDS PAGE
Format: Purified antibody in PBS pH 7.2. Sterile filtered
Applications: ELISA, WB. Other uses not tested
Storage: 4°C for short term and -20°C for long term. Avoid frequent freeze and thaw.
Stability: 60 months at -20°C.
Shipping: Products may be shipped on ice pack.
Usage: ARC products are intended for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, diagnostic, agricultural or pesticidal, food additives or as household chemicals.