Anti-Galactosylceramide Antibody

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Anti-Galactosylceramide Antibody

Product Name: Anti-Galactosylceramide Antibody

Catalogue No.: 164520

Alternate Names: Galactocerebroside, N-(hexadecanoyl)-1-beta-galactosyl-sphing-4-enine, N-

Description: Galactosylceramides are a sphingolipid with one carbohydrate moiety attached to a
ceramide unit. Galactosylceramide is the principal glycosphingolipid in brain tissue, hence the trivial name cerebroside. Galactosylceramides are found in all nervous tissues. They can amount to 2% of the dry weight of grey matter and 12% of white matter. They are major constituents of oligodendrocytes. A defect in the degradation of cerbrosides leads to a disorder called Krabbe disease. Krabbe disease (also known as globoid cell leukodystrophy or galactosylceramide lipidosis) is a rare, often fatal degenerative disorder that affects the myelin sheath of the nervous system. Krabbe disease is caused by mutations in the GALC gene, which causes a deficiency of galactosylceramidase.

Immunogen: Galactosylceramide linked to carrier.

Host: Rat.

Clonality: Polyclonal IgG.

Specificity: Universal. Cross reactivity not tested.

Concentration: 1.2mg/mL IgG.

Purity: Glucosylceramide affinity purified rat IgG to >95% (by SDS PAGE).

Format: Provided as a sterile filtered solution in PBS, pH 7.2. No other additives.

Uses: Competitive ELISA, WB. Not tested for other uses.

Storage: Store at 4oC in fridge a for short term use. Aliquot and store at -20oC or -80oC for long term storage. Avoid repeated freeze thaw cycles.

Shipping: Antibody is shipped on ice pack at ambient temperature.