Product Name: Anti Gram Positive Bacterial LTA Antibody
Catalogue No.: 164508
Alternate Names: Lipoteichoic acid, Lipoteichoicacid
Description: Lipoteichoic acid (LTA) is a major immunostimulatory component of cell wall of Gram-positive Bacteria. These organisms have an inner (or cytoplasmic) membrane and, external to it, a thick peptidoglycan layer. LTA is anchored to the cell membrane via diacylglycerol. Like LPS, LTA is an amphiphile formed by a hydrophilic polyphosphate polymer linked to a neutral glycolipid. LTA stimulates immune cells through TLR2 to produce TNF-α and other inflammatory cytokines. Recognition of LTA involves also LPS-binding protein (LBP) and CD14.
Immunogen: LTA linked to carrier.
Clonality: Polyclonal IgG.
Specificity: Gram Positive Bacteria
Concentration: 1.2mg/mL IgG.
Purity: LTA affinity purified rat IgG to >95% (by SDS PAGE).
Format: Provided as a sterile filtered solution in PBS, pH 7.2. No other additives.
Uses: Competitive ELISA, WB. Not tested for other uses.
Storage: Store at 4°C in fridge a for short term use. Aliquot and store at -20°C or -80°C for long term storage. Avoid repeated freeze thaw cycles.
Shipping: Antibody is shipped on ice pack at ambient temperature.