Product: Anti Human HSD 17B7 Native Protein Polyclonal Antibody
Catalogue No.: 831075
Alternate Names: 17-beta-hydroxysteroid dehydrogenase 7; Hydroxysteroid dehydrogenase 17beta, type 7Protein; 3-keto-steroid reductase, Estradiol 17 beta dehydrogenase 7; PRAP; SDR37C1; Short chain dehydrogenase/reductase family 37C member 1
Description: HSD17B7 is involved in steroid biosynthesis, functioning in estrogen biosynthesis by converting weak estrogen to potent estradiol. A second function is in cholesterol biosynthesis responsible for conversion of zymosterol from lanosterol, step 5/6. Responsible for the reduction of the keto group on the C-3 of sterols. Most abundant in ovaries of pregnant animals, specifically in corpus luteum of pregnancy. Present also in non-pregnant animals in ovaries (follicles), placenta, breast cancer, mammary gland, liver, kidney, testis and MCF-7 cell line. Genbank Accession NM_010476, molecular weight 33kDa.
Immunogen: Human recombinant protein
Specificity: Human, Mouse, Rat. Not tested for other species.
Format: Hyper immune sera with 0.05% azide
Uses: Western blot (WB), Immuno fluorescence (IF), Immuno precipitation (IP), Immune Histo chemistry. Not tested for other uses.
Storage: In lyophilized form, for long periods, store at 4oC in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20oC.
Shipping: Antibody is shipped lyophilized at ambient temperature.