Product: Anti Mouse HSD 20 Alpha Polyclonal Antibody
Catalogue No.: 831077
Alternate Names: 20α-hydroxysteroid dehydrogenase; 20 alpha-HSD, Aldo-ketoreductase family 1 member C18, 20 alpha-hydroxy steroid dehydrogenase, and 20 alpha-HSDH
Description: HSD 20A catalyzes the conversion of progesterone to its inactive form, 20α-hydroxyprogesterone. This enzyme controls progesterone homeostasis during pregnancy and its activity is down regulated by prolactin in the corpus luteum of pregnancy until 24 hour prior to parturition when luteolysis takes place. In addition, it is induced in hematopoietic cells and is used as an assay for the identification of T cell derived factor interleukin-3. Other than its function in progesterone inactivity and T-cells, 20α-HSD enzyme reduces and inactivates 17-deoxycorticosterone, the precursor of aldosterone and corticosterone. Genbank Accession number AB059565, Molecular weight 37kDa.
Immunogen: Native mouse protein
Specificity: Mouse, Rat. Not tested for other species.
Format: Hyper immune sera with 0.05% azide.
Uses (verified): WB, Immuno fluorescence (IF), Immune Histo chemistry (IHC).
Storage: In lyophilized form, for long periods, store at 4oC in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20oC.
Shipping: Antibody is shipped lyophilized at ambient temperature.