Product Name: Anti-Human CASR Antibody
Catalogue No.: 164515
Alternate Names: Calcium Sensing Receptor, Parathyroid Cell Calcium-Sensing Receptor 1, GPRC2A, PCAR1, HCasR, CAR, Extracellular Calcium-Sensing Receptor, Parathyroid Ca(2+)-Sensing Receptor 1, Severe Neonatal Hyperparathyroidism, Hypocalciuric Hypercalcemia 1, Calcium-Sensing Receptor, HYPOC1, NSHPT, EIG8, HHC1, FHH, FIH, HHC.
Description: This is a G protein-coupled receptor that senses small changes in circulating calcium concentration. The encoded protein couples this information to intracellular signaling pathways that modify parathyroid hormone secretion or renal cation handling, and thus this protein plays an essential role in maintaining mineral ion homeostasis. Mutations in this gene are a cause of familial hypocalciuric hypercalcemia, neonatal severe hyperparathyroidism, and autosomal dominant hypocalcemia. Diseases associated with CASR include Hypocalcemia, Autosomal Dominant 1, and Hyperparathyroidism.
Immunogen: N-terminal Peptide
Clonality & Isotype: Monoclonal IgG1, k
Clone ID: HL1499
Specificity: Human, Mouse, Rat, Rabbit. Other species not tested.
Format: Provided as affinity purified and sterile filtered antibody in PBS, pH7.2
Purity: Affinity purified antibody. >90% pure by SDS PAGE
Uses (Verified): ELISA, WB, IP, IF. Other uses not tested
Optimal dilution to be determined by used, starting at 1:1000.
Storage: Store at 4°C for short term and -20°C for long term.
Make aliquots as needed. Avoid frequent freeze and thaw cycles.
Stability: 24 months at -20°C.
Shipping: Products may be shipped on ice pack.