Product: Anti Human Tau
Catalogue No.: 111112
Alternate Names: AI413597 antibody
Disinhibition dementia parkinsonism amyotrophy complex antibody
FTDP 17 antibody
G Protein beta 1 gamma 2 subunit interacting factor 1 antibody
G protein beta1/gamma2 subunit interacting factor 1 antibody
Microtubule associated protein tau antibody
Microtubule associated protein tau isoform 4 antibody
Microtubule-associated protein tau antibody
Neurofibrillary tangle protein antibody
Paired helical filament tau antibody
Paired helical filament-tau antibody
PHF tau antibody
Tauopathy and respiratory failure, included antibody
Description: Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
Immunogen: Synthetic peptide corresponding to human Tau surrounding Serine 262
Format: Provided as a sterile filtered purified antibody in PBS pH 7.2. No additives.
Purity: Affinity purified antibody, >90% pure by SDS PAGE.
Applications: ELISA, WB, IHC. Other uses not tested.
Storage: 4°C - 8°C for short term use and -20°C -80°C for long term storage. May be made
into aliquots for storage. Avoid frequent freeze and thaw.
Stability: 60 months at -20°C if stored as recommended.
Shipping: Products may be shipped on ice pack.
Usage: ARC products are intended for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, diagnostic, agricultural or pesticidal, food additives or as household chemicals.