Product Name: Anti-Human N/H/K-Ras Antibody
Catalogue No.: 162448
Other Names: NRAS, HRAS1, GTPase NRas, transforming protein N-Ras, HRAS, HRAS1, GTPase HRas, H-Ras-1, Ha-Ras, Transforming protein p21, c-H-ras, p21ras, KRAS, KRAS2, RASK2, GTPase KRas, K-Ras 2, Ki-Ras, c-K-ras, c-Ki-ras
Description: This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region.
Immunogen: Recombinant protein
Clonality: Polyclonal IgG
Specificity: Human other species not tested
Purity: Protein-A affinity purified rabbit IgG to >95% (by SDS PAGE). Highly specific.
Format: Provided in PBS with 0.02% Sodium Azide, 0.5% BSA and 50% Glycerol.
Uses: Suggested dilutions - ELISA (1:10,000), WB (1:1000), IHC (1:100). Optimal dilution for a specific application should be determined. Not tested for other uses.
Storage: Store at -20oC. Avoid repeated freeze thaw cycles.
Shipping: Antibody is shipped on ice pack at ambient temperature.