Anti N/H/K-Ras Polyclonal Antibody

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Anti N/H/K-Ras Polyclonal Antibody

Product Name: Anti-Human N/H/K-Ras Antibody

Catalogue No.: 162448

Other Names: NRAS, HRAS1, GTPase NRas, transforming protein N-Ras, HRAS, HRAS1, GTPase HRas, H-Ras-1, Ha-Ras, Transforming protein p21, c-H-ras, p21ras, KRAS, KRAS2, RASK2, GTPase KRas, K-Ras 2, Ki-Ras, c-K-ras, c-Ki-ras

Description: This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region.

Immunogen: Recombinant protein

Host: Rabbit

Clonality: Polyclonal IgG

Specificity: Human other species not tested

Purity: Protein-A affinity purified rabbit IgG to >95% (by SDS PAGE). Highly specific.

Format: Provided in PBS with 0.02% Sodium Azide, 0.5% BSA and 50% Glycerol.

Uses: Suggested dilutions - ELISA (1:10,000), WB (1:1000), IHC (1:100). Optimal dilution for a specific application should be determined. Not tested for other uses.

Storage: Store at -20oC. Avoid repeated freeze thaw cycles.

Shipping: Antibody is shipped on ice pack at ambient temperature.