Product: Anti Equine IgA Polyclonal Antibody
Catalog No.: 165262
Description: Horses have 11 immunoglobulin isotypes: IgM, IgD, IgA, IgE, and seven IgG subclasses designated as IgG1–IgG7, each of which are distinguished by separate genes encoding the constant heavy chain regions. Immunoglobulin (Ig)isotypes have different functions during the immune response and pathogen-specific isotypes can be used as indicator for immunity and protection from disease. IgA is present in both the serum and mucosal secretions of the horse, and it is the principal Ig in milk, tears, and secretions of the upper respiratory tract. In common with most other mammalian species, the horse has a single IgA heavy chain constant region gene (IGHA). A mucosal IgA response in horses makes a key contribution to immunity against viral (Equine Influenza virus and Equine herpes virus-1) and bacterial (S. equi, Rhodococcus equi, Salmonella enterica, and Clostridium botulinum) infections.
Immunogen: Purified Equine IgA.
Host: Rat.
Clonality: Polyclonal.
Specificity: Horse.
Concentration: 1.0 mg/ml.
Purity: Affinity purified to greater than 95% (by SDS PAGE).
Format: Provided as a sterile filtered solution in PBS, pH 7.2. No other additives.
Uses: ELISA, WB, IHC. Other uses not tested.
Storage: Store at 4°C in the fridge for short term use. Aliquot and store at <-20°C for long term storage. Avoid repeated freeze thaw cycles.
Stability: 60 months at <-20°C.
Shipping: Products may be shipped on ice packs at ambient temperature.
