Description
Product Name: 2OhdG (8-hydroxydeoxyguanosine)
Catalog No.: 900102
Alternate Names: 8-OHdG, 8-Hydroxy-2’-deoxyguanosine, 8-Oxo-2’-deoxyguanosine, 8-Oxo-dG, 8-Hydroxydeoxyguanosine
Description: 8-Hydroxy-2’-deoxyguanosine (8-OHdG) is a well-known Biomarker of oxidative DNA damage generated by the oxidation of guanine residues in DNA by reactive oxygen species (ROS). It is widely used in biomedical, toxicological, and environmental research to assess oxidative stress levels and DNA damage associated with aging, cancer, cardiovascular diseases, neurodegenerative disorders, and various inflammatory conditions. Quantification of 8-OHdG in biological samples such as urine, serum, plasma, and tissue extracts provides valuable insights into cellular oxidative damage and the effectiveness of antioxidant defense mechanisms.
Molecular Formula: C₁₀H₁₃N₅O₅
Quantity: 1 mg
Appearance: White to off-white crystalline powder
Molecular Weight: 283.24 g/mol
Purity (Assay by HPLC): >98.0%
Melting Point: 220°C – 225°C (decomposes)
Solubility: Soluble in water and aqueous buffers; slightly soluble in methanol and ethanol
