Anti Galactosylceramide (Cerebroside) Pab

$595.00
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SKU:
164520
Size:
100ug
Anti Galactosylceramide (Cerebroside) Pab

Product: Anti-Galactosylceramide Polyclonal Antibody

Catalog No.: 164520

Alternate Names: Galactocerebroside, N-(hexadecanoyl)-1-beta-galactosyl-sphing-4-enine, N-(hexadecanoyl)-1-b-galactosyl-sphing-4-enine.

Description: Galactosyl Ceramides are a sphingolipid with one carbohydrate moiety attached to a ceramide unit. Galactosylceramide is the principal glycosphingolipid in brain tissue, hence the trivial name cerebroside.  Galactosyl Ceramides are found in all nervous tissues. They can amount to 2% of the dry weight of grey matter and 12% of white matter. They are major constituents of oligodendrocytes.  A defect in the degradation of cerebrosides leads to a disorder called Krabbe disease. Krabbe disease (also known as globoid cell leukodystrophy or galactosylceramide lipidosis) is a rare, often fatal degenerative disorder that affects the myelin sheath of the nervous system. Krabbe disease is caused by mutations in the GALC gene, which causes a deficiency of galactosylceramidase. 

Immunogen: Galactosylceramide linked to carrier.

Host: Rabbit.

Clonality: Polyclonal.

Specificity: Universal. Cross reactivity not tested. 

Concentration:1.0 mg/ml.

Purity: Affinity purified rabbit IgG to >95% (by SDS PAGE).  

Format: Provided as a sterile filtered solution in PBS, pH 7.2. No other additives. 

Uses: Competitive ELISA, WB. Not tested for other uses. 

Storage: Store at 4°C in the fridge for short term use. Aliquot and store at -20°C or -80°C for long term storage. Avoid repeated freeze thaw cycles.

Shipping: Antibody is shipped on an ice pack at ambient temperature.

Galactosylceramide