Product: Anti Ganglioside GM2 Polyclonal Antibody
Catalog No.: 163068
Description: Gangliosides are complex glycolipids composed of a ceramide linked to a glycan with at least one sialic acid. In humans, GM3 ganglioside is predominantly in peripheral tissues such as liver, adipose tissue, aorta, and platelets ; whereas GM1, GD1a, GD1b, GT1b, and GQ1b are the major gangliosides in human brain (~95%). The remaining 5% of brain gangliosides corresponds to other gangliosides among which GM2 is found. Gangliosides are distributed in caveolae-rich microdomains of the plasma membrane, where they perform crucial functions such as membrane organization, neuronal differentiation, cell adhesion, signal transduction, inflammation, and neurite outgrowth, among others.
Immunogen: GM2 covalently linked to a carrier protein
Clonality: Polyclonal
Host: Rat
Concentration: 1.2 mg/ml
Specificity: Universal. Cross reactivity not tested
Purity: Protein-A affinity purified IgG, >90% pure by SDS PAGE
Format: Provide as purified antibody in neutral buffer, sterile filtered
Uses (Verified): ELISA, WB, IHC. Other uses not tested.
Stability: 60 months at -80°C.
Storage: Aliquot and store at -20°C or -80°C for the long term. May be stored at refrigerator for short term use. Minimize freezing and thawing.
Shipping: Products may be shipped on ice packs at ambient temperature.
