Product: Anti Mouse IgG1 Monoclonal Antibody
Catalog No.: 165274
Description: IgG1 is the most abundant IgG subclass in the serum; its hinge region contains 15 aa and possesses 2 disulfide bonds linking the HCs. Upon binding to their antigen, IgG1 forms immune complexes that activate the complement cascade through the classical pathway initiated by the C1q molecule. Complement activation leads to (i) cell lysis through the membrane attack complex, (ii) inflammation through the generation of anaphylatoxins and chemoattractant, and (iii) immune complex clearance. Therefore, complement activation by immune complexes is a key event to the response against pathogens.
Immunogen: Purified Mouse IgG1.
Host: Rat.
Clonality: Monoclonal.
Specificity: Mouse.
Concentration: 1.0 mg/ml.
Purity: Affinity purified to greater than 95% (by SDS PAGE).
Format: Provided as a sterile filtered solution in PBS, pH 7.2. No other additives.
Uses: ELISA, WB, IHC. Other uses not tested.
Storage: 4°C for short term and <-20°C for long term. Avoid frequent freezing and thawing.
Stability: 60 months at <-20°C.
Shipping: Products may be shipped on ice packs at ambient temperature.
![Anti Mouse IgG1 Mab [10.9]](https://cdn11.bigcommerce.com/s-e7c5fvpp1c/images/stencil/500x659/products/296443/287386/monoclonal__15701.1678817942.png?c=2 "Anti Mouse IgG1 Mab [10.9]")
