Product: Anti Thioredoxin
Catalogue No.: 111107
Alternate Names: ADF antibody, ADF antibody, ATL derived factor antibody, ATL-derived factor Antibody, DKFZp686B1993 antibody, MGC61975 antibody, SASP antibody, Surface associated sulphydryl protein antibody, Surface associated sulphydryl protein antibody, Surface-associated sulphydryl protein antibody, THIO_HUMAN antibody, Thioredoxin antibody, TRDX antibody, TRX 1 antibody, Trx antibody, TRX1 antibody, TXN antibody, TXN protein antibody, TXN protein antibody, zgc:92903 antibody.
Description: Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Induces the FOS/JUN AP-1 DNA-binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity. ADF augments the expression of the interleukin-2 receptor TAC (IL2R/P55).
Immunogen: Synthetic peptide conjugated to KLH derived from within residues 50 to the C-terminus of Human Thioredoxin/ TRX.
Host: Rabbit
Clonality: Polyclonal
Concentration: 1mg/mL
Format: Provided as a sterile filtered purified antibody in PBS pH 7.2. No additives.
Purity: Affinity purified antibody, >90% pure by SDS PAGE.
Applications: ELISA, WB, IHC. Other uses not tested.
Storage: 4°C - 8°C for short term use and -20°C -80°C for long term storage. May be made into aliquots for storage. Avoid frequent freeze and thaw.
Stability: 60 months at -20°C if stored as recommended.
Shipping: Products may be shipped on ice pack.
