Anti EBV Early Antigens (Epstein Barr Virus) Mab [1108-1]

Product Name: Anti EBV Early Antigens Antibody [1108-1]

Catalogue No.: 632810

Alternate Names: EBNA1; EBV nuclear antigen 1; Epstein Barr nuclear antigen 1; Human Herpesvirus 4 (HHV4)

Description: Epstein-Barr virus (EBV), also designated human herpesvirus 4 (HHV-4), is a member of the herpesvirus family and is one of the most common human viruses. EBV infects B cells and, though often asymptomatic, it can cause infectious mononucleosis, a disease characterized by fatigue, fever, sore throat and muscle soreness. The EBV-induced early antigens (Ea) are among several antigen complexes that have been identified in EBV-infected cells. The Ea complex is composed of diffuse (Ea-D) and restricted (Ea-R) components. The activity of Ea-D is suppressed during latent infection. BMRF1, the gene that encodes for Ea-D, is closely associated with the gene encoding for EBV DNA polymerase, and Ea-D is essential for the activity of this polymerase. Ea-D forms a complex with EBV DNase and, together, they may play a role in viral replication.

Immunogen: Affinity purified early antigen polypeptides from induced Raji cells precipitated with African Burkitt’s lymphoma sera

Clonality: Monoclonal

Host: Mouse

Specificity: EBV

Concentration: 0.2mg/mL

Purity: >90% pure by SDS PAGE

Format: Provide in PBS with 0.05% BSA and 0.05% sodium azide

Applications: Immunofluorescence (0.5-1ug/ml);
Western Blotting (0.5-1.0ug/ml); Immunoprecipitation (0.5-1µg/500ug protein lysate);
Immunohistology (Frozen) (0.5-1.0ug/ml for 30 minutes at RT)
Optimal dilution for a specific application should be determined.

Stability: Stable for 24 months is stored as recommended.

Storage: Store at 2-8°C refrigerator for short term use. Aliquot and store at -20°C or –
80°C for long term. Minimize freezing and thawing.

Shipping: Products may be shipped on ice pack.