Product: Anti Glucosyl-Ceramide Polyclonal Antibody
Catalog No.: 111586
Alternate Names: GL1, GluCer, Glucosyl ceramide, Cerebroside, Glucocerebroside, Glucosyl-ceramide, Glucoceramide, Glucoceramide, Glucocerebroside
Description: Glucosylceramide is found at low levels in animal cells such as the spleen, erythrocytes, and nervous tissues. It is a major constituent of skin, where it is essential for lamellar body formation in the stratum corneum and to maintain the water permeability barrier of the skin. It is a major component of the outer layer of the plasma membrane. Glucosylceramide is the only glycosphingolipid common to plants, fungi and animals. It is usually considered to be the principal glycosphingolipid in plants. Gaucher disease involves the accumulation of glucosylceramide and its deacylated lysolipid, glucosyl sphingosine (lyso-GL1) which is implicated in mediating immune dysregulation and skeletal disease.
Immunogen: Glucosylceramide is linked to the carrier.
Host: Rabbit.
Clonality: Polyclonal.
Specificity: Universal.
Concentration:1 mg/mL IgG.
Purity: Affinity purified rabbit IgG to >95% (by SDS PAGE).
Format: Provided as a sterile filtered solution in PBS, pH 7.2. No other additives.
Uses: ELISA, WB, IHC. Not tested for other uses.
Storage: Store at 4°C in the fridge for short term use. Aliquot and store at -20°C or -80°C for long term storage. Avoid repeated freeze thaw cycles.
Shipping: Antibody is shipped on an ice pack at ambient temperature.
