Product: Anti Pig IgM Polyclonal Antibody
Catalog No.: 165285
Description: It is the first immunoglobulin to be produced after the immune response takes place. IgM is the predominant isotype in the primary response. IgM is the second most abundant immunoglobulin in the serum, after IgG. It represents 10-12% of the total porcine immunoglobulin. The role of the IgM is essential as that of the first immunoglobulin to be produced in the humoral response. Even though its affinity to bind antigens is smaller than that of IgG, its pentameric structure allows it to bind in a multiple ways to antigens and so activates the complement cascade. Just one pentameric molecule of IgM, once bound to the antigen, is able to initiate both complement cascade and phagocytosis. IgM is particularly effective against a huge number of gram negative bacteria and it can neutralize viral agents. Due to its big size, it is mainly present in the blood serum.
Immunogen: Purified Pig IgM.
Host: Rat.
Clonality: Polyclonal.
Specificity: Porcine.
Concentration: 1.0 mg/ml.
Purity: Affinity purified to greater than 95% (by SDS PAGE).
Format: Provided as a sterile filtered solution in PBS, pH 7.2. No other additives.
Uses: ELISA, WB, IHC. Other uses not tested.
Storage: Store at 4°C in the fridge for short term use. Aliquot and store at <-20°C for long term storage. Avoid repeated freeze thaw cycles.
Stability: 60 months at <-20°C.
Shipping: Products may be shipped on ice packs at ambient temperature.
