Product: Rat IgG4 Native Protein
Catalog No.: 117494
Lot No: As listed in vial
Alternate Names: IgG4, Immunoglobulin-G4
Description: IgG4 plays a protective role in allergy by acting as a blocking antibody, and inhibiting mast cell degranulation, but a deleterious role in malignant melanoma, by impeding IgG1-mediated anti-tumor immunity. These findings highlight the importance of understanding the interaction between IgG4 and Fcγ receptors.
Type: Native Protein
Source: Rat Hybridoma
Concentration: >1 mg/mL
Molecular Weight: ~150,000 Da
Appearance: Clear solution
Format: Provided as sterile filtered solution in PBS, pH 7.2. No preservatives added.
Purity: Protein-A Affinity purified to greater than 95%. Validated by SDS-PAGE.
Validated Uses: ELISA, WB, IP, IHC. For laboratory research use only
Storage: Store at 4°C in the fridge for short term use. Aliquot and store at -20°C or -80°C for long term storage. Avoid repeated freeze thaw cycles.
Stability: Stable for 60 months stored at recommended storage conditions.
Shipping: Antibody may be shipped on ice packs at ambient temperature.