Product: Anti Ganglioside GM2 Polyclonal Antibody
Catalog No.: 163067
Description: Gangliosides are complex glycolipids composed of a ceramide linked to a glycan with at least one sialic acid. In humans, GM3 ganglioside is predominantly in peripheral tissues such as liver, adipose tissue, aorta, and platelets ; whereas GM1, GD1a, GD1b, GT1b, and GQ1b are the major gangliosides in human brain (~95%). The remaining 5% of brain gangliosides corresponds to other gangliosides among which GM2 is found. Gangliosides are distributed in caveolae-rich microdomains of the plasma membrane, where they perform crucial functions such as membrane organization, neuronal differentiation, cell adhesion, signal transduction, inflammation, and neurite outgrowth, among others.
Immunogen: GM2 covalently linked to a carrier protein
Host: Rabbit.
Clonality: Polyclonal.
Specificity: Universal. Cross reactivity not tested.
Concentration: 1.2 mg/mL IgG.
Purity: Affinity purified total rabbit IgG to >95% (by SDS PAGE).
Format: Provided as a sterile filtered solution in PBS, pH 7.2. No other additives.
Uses: ELISA, WB, IHC. Not tested for other uses.
Storage: Store at 4°C in the fridge for short term use. Aliquot and store at -20°C or -80°C for long term storage. Avoid repeated freeze thaw cycles.
Stability: 60 months at -80°C
Shipping: Antibody is shipped on an ice pack at ambient temperature.
